High-level semi-synthetic production of the potent antimalarial artemisinin

By C. Paddon, Patrick Westfall, D. Pitera, Kirsten Benjamin, K. Fisher, D. McPhee, M. Leavell, Anna Tai, A. Main, Diana Eng and 40 more. Nature, 2013

1,882 citations recorded by the source corpus.

Subfields: Computational Theory and Mathematics, Molecular Biology, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/d08c609e61403925da388013dc31a195dded67fe

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In Molecular Biology

1. James C. Liao

Citations in the corpus

• Engineering Cellular Metabolism (2008, positive): “…heterologous expression requires enzyme discovery as part of 1186 Cell 164, March 10, 2016 ª2016 Elsevier Inc. the metabolic engineering program, as illustrated for production of artemisinic acid (Ro et al., 2006; Westfall et al., 2012; Paddon et al., 2013) and opioids (Galanie et al., 2015).”
• Discovery and resupply of pharmacologically active plant-derived natural products: A review (2015, methodology): “, and subsequent semi-synthetic conversion of artemisinic acid to artemisinin by a simple and inexpensive chemical conversion procedure (Paddon et al., 2013).”