Systemic delivery of genes to striated muscles using adeno-associated viral vectors

By P. Gregorevic, Michael J. Blankinship, J. Allen, R. Crawford, L. Meuse, Daniel G. Miller, David W. Russell, J. Chamberlain. Nature Medicine, 2004

637 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/d03bddd78b695459e307dbe9ccba1e78e67c7c42

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In Genetics

1. M. Kay

In Molecular Biology

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Citations in the corpus

• Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8. (2006, background): “first demonstrated its proof-of-principle with rAAV6 vectors [10].”
• Adeno-associated virus serotypes: vector toolkit for human gene therapy. (2006, background): “On the other hand, AAV6, which transduces skeletal muscle with high efficiency, may require coadministration of VEGF to traverse the blood vessel barrier and achieve whole-body transgene expression [70].”