Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention.

By R. Gansevoort, R. Correa-Rotter, B. Hemmelgarn, T. Jafar, H. Heerspink, J. Mann, K. Matsushita, C. Wen. The Lancet, 2013

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Global Prevalence of Chronic Kidney Disease – A Systematic Review and Meta-Analysis (2016, background): “[4, 17, 18] While this high (and rising (4),) prevalence is in part due to the ageing population, it is also associated with increases in hypertension and diabetes mellitus[1].”
Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy. (2017, background): “Therefore, there is obvious potential for developing a risk prediction tool that integrates CKD markers with traditional CVD risk factors, but the benefit of this approach would need to be demonstrated.(210)”
Gut Microbiota in Cardiovascular Health and Disease (2017, background): “People with CKD have a greater risk of CVD-related mortality.(129) The increased CVD risk is only partially explained by traditional cardiovascular risk factors, and there is increasing evidence that nontraditional risk factors such as inflammation, oxidative stress, and endothelial dysfunction play”