Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials.

By W. Hacke, G. Donnan, C. Fieschi, M. Kaste, R. Kummer, Joseph Broderick, T. Brott, Michael R. Frankel, J. Grotta, E. Haley and 14 more. The Lancet, 2004

2,663 citations recorded by the source corpus.

Subfields: Epidemiology, Neurology, Rehabilitation

View Paper: https://www.semanticscholar.org/paper/cf889954bac3ddbc036601cc5461c6cb65968361

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. M. Krenz
2. John P. A. Ioannidis
3. Ronald J. Korthuis
4. Christopher P. Baines
5. Theodore J Kalogeris

Citations in the corpus

• Guidelines for management of ischaemic stroke and transient ischaemic attack 2008. (2008, background): “Even with optimal stroke unit care including thrombolysis, fewer than one third of patients recover fully from stroke [386].”
• Contradicted and initially stronger effects in highly cited clinical research. (2005, result): “The findings of 20 highly cited articles (44%) were replicated (also with a larger sample size in subsequent research compared with the original highly cited study) and 11 (24%) had remained largely unchallenged.(58-78)”
• Cell Biology of Ischemia/Reperfusion Injury (2012, background): “Indeed, optimal results are observed if thrombolytic therapy is initiated within the first 90 min after the onset of symptoms (Hacke et al., 2004).”
• Multisociety Consensus Quality Improvement Revised Consensus Statement for Endovascular Therapy of Acute Ischemic Stroke (2018, positive): “Reperfusion treatment (intravenous or endovascular) achieved within the shortest period of time is widely accepted as a prerequisite for optimal clinical outcomes (45,84,85).”