T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development.
By Naganari Ohkura, M. Hamaguchi, Hiromasa Morikawa, K. Sugimura, Atsushi Tanaka, Yoshinaga Ito, Motonao Osaki, Yoshiaki Tanaka, R. Yamashita, N. Nakano and 5 more. Immunity, 2012
716 citations recorded by the source corpus.
Subfields: Immunology
View Paper: https://www.semanticscholar.org/paper/5d1ed38db7f3100f5c6ffe9b8e514950549b4713
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In Immunology
- Atsushi Tanaka
- Naganari Ohkura
- J. Wing
- K. Ichiyama
- N. Mikami
- Shimon Sakaguchi
- Y. Kitagawa
- Alexander Y. Rudensky
Citations in the corpus
- Regulatory T Cells and Human Disease. (2020, background): “The Treg-specific DNA demethylation pattern similarly occurs in pTregs, which are mainly found in intestinal mucosal tissues and also induced from someTconvs by homeostatic expansion in a T cell–deficient environment (42).”
- Development and maintenance of regulatory T cells. (2013, background): “In contrast, the acquisition of Treg-cell-specific DNA hypomethylation appears to depend on the duration of TCR stimulation (Ohkura et al., 2012).”