Spatio-temporal point-spread function of fMRI signal in human gray matter at 7 Tesla

By Amir Shmuel, Essa Yacoub, D. Chaimow, Nikos K. Logothetis, Kamil Ugurbil. NeuroImage, 2007

309 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/cf3d4772a787e82477c7a926391ebf12d7313d47

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Citations in the corpus

The Minimal Preprocessing Pipelines for the Human Connectome Project (2013, background): “Such low frequency correction does not affect the discriminability of neighboring cortical areas with differing myelin contents, whose boundaries exist at a much higher spatial frequency than a sigma of ~14 mm(FWHM = ~33 mm).”
Pushing spatial and temporal resolution for functional and diffusion MRI in the Human Connectome Project (2013, background): “This confound can be reduced by restricting analysis to gray-matter voxels (e.g., Formisano et al., 2004; Kolster et al., 2010; Shmuel et al., 2007), but it is not eliminated because the BOLD effect extends outside vascular boundaries by about the blood vessel diameter (Ogawa et al., 1993).1 If the…”
Robust detection of ocular dominance columns in humans using Hahn Spin Echo BOLD functional MRI at 7 Tesla (2007, methodology): “Finally, the point-spread-function (PSF) of the GE BOLD response in gray matter was shown to be approximately time invariant 4 s after stimulation onset (Shmuel et al., 2007), thus, significantly limiting the window of data acquisition where spatial specificity might be gained.”
Overview of Functional Magnetic Resonance Imaging (2011, background): “Other experiments have reported the use of spin echo rather than gradient echo acquisitions of BOLD contrast, especially at higher fields where T2* is foreshortened.(22) While a modest research effort will continue in improving acquisition technology, the bulk of research in the development of fMRI ”
The WU-Minn Human Connectome Project: An Overview (2013, background): “Additionally, higher fields increase the relative sensitivity to the microvasculature in BOLD-based functional images (Ogawa et al., 1993; Ugurbil et al., 2003; Uludag et al., 2009), resulting in a smaller point spread function (Shmuel et al., 2007).”
High-field fMRI unveils orientation columns in humans (2008, methodology): “We recently reported that when avoiding large vessels, the point spread function (PSF) (Gaussian, full-width half-maximum) of GE BOLD signals at 7 T has an upper limit of 2 mm (49), consistent with a GE-BOLD PSF of 1.”
An integrative model for neuronal activity-induced signal changes for gradient and spin echo functional imaging (2009, methodology): “Nonetheless, one should be aware that the discussion of relative contribution of micro- and macro-vasculature does not address the question of physical point-spread-function (PSF) of MRI (e.g. Shmuel et al., 2007).”
Laminar analysis of 7 T BOLD using an imposed spatial activation pattern in human V1 (2010, methodology): “Previous studies [e.g., Engel et al., 1997; Menon & Goodyear, 1999; Leite et al., 2004; Shmuel et al., 2007] have reported measures of PSFtang taken by inducing spatial activation patterns in the visual cortex.”
Resting-state fMRI in the Human Connectome Project (2013, background): “, 2001), significantly reducing the point spread function of the BOLD response; an upper limit of 2 mm FWHM was measured at 7 T (Shmuel et al., 2007).”
Population receptive field estimates in human visual cortex (2008, background): “In the future, with more precise estimates of the HRF across cortex, it should be possible to extend the HRF analysis to include the spatial component (3–4 mm fullwidth at half-maximum along the cortical surface (Das and Gilbert, 1995; Engel et al., 1997; Iadecola et al., 1997; Malonek and Grinvald,”