Size of treatment effects and their importance to clinical research and practice.

By H. Kraemer, David J. Kupfer. Biological Psychiatry, 2006

841 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/ceebbf21baa000576a2da370bc56fdfaecec8926

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Statistics and Probability

Citations in the corpus

Internet and Computer-Based Cognitive Behavioral Therapy for Anxiety and Depression in Youth: A Meta-Analysis of Randomized Controlled Outcome Trials (2015, methodology): “Given the difficulty of interpreting the standardized mean difference (Hedges ’ g) from a clinical perspective, we transformed these values into the number-needed-to-treated (NNT) using the formula provided by Kraemer and Kupfer [37].”
Emotion Regulation and Posttraumatic Stress Disorder: A Prospective Investigation (2013, result): “Given the nature of our population (i.e., severe PTSD in need of residential treatment), we posit that these results are clinically meaningful (Kraemer & Kupfer, 2005).”
Supporting thinking on sample sizes for thematic analyses: a quantitative tool (2015, background): “Table 1 shows the samples sizes required for 80% power, which is a level commonly used in quantitative studies (Cohen, 1992; Kraemer & Kupfer, 2006; Senn & Bretz, 2007), and Table 2 for 90% power to discover themes with a range of values for population prevalence.”
The Benefit of Web- and Computer-Based Interventions for Stress: A Systematic Review and Meta-Analysis (2017, positive): “Because of the difficulty of interpreting Cohen d from a clinical perspective, we also transformed these values into numbers needed to treat (NNT) according to the formula of Kraemer and Kupfer [44].”
Predictive validity performance indicators in violence risk assessment: a methodological primer. (2013, background): “…potential pitfall is that the NND and NSD rely on the use of a single cut-off threshold, though formulae for the statistical conversion from alternative performance indicators to the NNT may be adapted to help address this (Furukawa, 1999; Hilton, Reid, & Paratz, 2006; Kraemer & Kupfer, 2006).”
Computer Therapy for the Anxiety and Depressive Disorders Is Effective, Acceptable and Practical Health Care: A Meta-Analysis (2010, methodology): “Because the effect size is not easy to interpret from a clinical point of view, we also calculated the NNT by transforming the effect sizes based on Z scores using the formulae provided by Kraemer and Kupfer [19].”