Prognostic Value of Troponins in Acute Pulmonary Embolism: A Meta-Analysis

By C. Becattini, M. Vedovati, G. Agnelli. Circulation, 2007

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Troponin elevation in coronary vs. non-coronary disease. (2011, neutral): “Becattini et al.54 has performed a meta-analysis of 20 studies in 1985 patients with PE.”
2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS) (2019, background): “0).(195) On their own, increased circulating levels of cardiac troponins have relatively low specificity and positive predictive value for early mortality in normotensive patients with acute PE.”
[2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism]. (2014, positive): “covering a total of 1985 patients showed elevated cardiac troponin I or -T concentrations in approximately 50% of the patients with acute PE (Table 8).(239) Elevated troponin concentrations were associated”
ESC Guidelines on the diagnosis and management of acute pulmonary embolism (2014, background): “or -T concentrations in approximately 50% of the patients with acute PE (Table 8).(239) Elevated troponin concentrations were associated with high mortality both in unselected patients [odds ratio (OR) 9.”