Comparison of Drug Adherence Rates Among Patients with Seven Different Medical Conditions

By B. Briesacher, S. Andrade, H. Fouayzi, K. Chan. Pharmacotherapy, 2008

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Comparing Adherence and Persistence Across 6 Chronic Medication Classes (2009, background): “However, the majority of previous studies have been limited to a single drug class or therapeutic area.5,7-11,17,21-22,26 In one exception, Briesacher et al. (2008) used pharmacy claims database records to study MPRs—but not persistence—among 7 disease cohorts (gout, hypercholesterolemia,…”
2012 American College of Rheumatology Guidelines for Management of Gout Part II: Therapy and Anti-inflammatory Prophylaxis of Acute Gouty Arthritis (2012, result): “Acute gout attacks attributable to the initiation of ULT may contribute to nonadherence in long-term gout treatment, as reported in recent studies (8).”
Self-report measures of medication adherence behavior: recommendations on optimal use (2015, background): “Other large studies crossing multiple chronic conditions and drug classes report nonadherence rates around 40–60 % [25, 28, 29], suggesting that approximately one of every two prescription doses are missed.”
Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study (2014, background): “[41] Such poor adherence to ULT has long been recognised, one review finding adherence in gout patients to be the worst of seven chronic diseases requiring chronic medication.[42] Nevertheless, we did find an encouraging signal of a 40% improvement in percentage of adherent patients from 1997 to 201”