Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular…

By J. Reynolds, A. Joannides, J. Skepper, R. McNair, L. Schurgers, D. Proudfoot, W. Jahnen-Dechent, P. Weissberg, C. Shanahan. Journal of the American Society of Nephrology, 2004

956 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Nephrology, Surgery

View Paper: https://www.semanticscholar.org/paper/ce30add1dd2486dc5b9a056afb5b4683b167f8b1

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. A. Durham
2. M. Scatena
3. Mei Y. Speer
4. C. Shanahan
5. C. Giachelli
6. W. Jahnen-Dechent
7. M. Ketteler

Citations in the corpus

• Magnesium basics (2012, background): “While calcium is a powerful ‘death trigger’ [35], magnesium is not [34]: magnesium inhibits calcium-induced cell death [36].”
• Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness (2018, background): “It has been shown that inhibition of apoptosis, for example by caspase inhibitors, significantly reduces both calcifying vesicle release and calcification.(77) Apoptosis occurs prior to calcification in vitro and apoptotic bodies are thought to contain high concentrations of calcium, which is ultima”