Mesoporous silica nanoparticles for intracellular delivery of membrane-impermeable proteins.

By Igor I. Slowing, B. Trewyn, V. S. Lin. Journal of the American Chemical Society, 2007

742 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/cda6d4c09e0c2cd56e9f992e45f232c5420bc48d

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomedical Engineering

1. Igor I. Slowing
2. Juan L. Vivero-Escoto
3. V. S. Lin

In Molecular Biology

1. Juan L. Vivero-Escoto
2. Igor I. Slowing
3. V. S. Lin
4. Chia-Wen Wu

Citations in the corpus

• Better safe than sorry: Understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications. (2010, background): “MCM-41 (2D-hexagonal) particles prepared with cationic surfactants thus displayed low toxicity when introduced into HeLa cell cultures [75,76].”
• Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers. (2008, background): “Recently, we demonstrated the use of pore expanded MSN to deliver a membrane-impermeable protein (cytochrome c) into HeLa cells, thereby showing that not only small drugs, but also macromolecules can be delivered with MSN-based systems [26].”
• Mesoporous Silica Nanoparticles: A Comprehensive Review on Synthesis and Recent Advances (2018, background): “Scientists have successfully worked on the utilization of these carriers for loading variety of cargo ranging from drugs to macromolecules such as proteins [23,24], DNA [25,26] and RNA [27,28].”