The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis.

By A. Yokoyama, T. Somervaille, Kevin S. Smith, O. Rozenblatt-Rosen, Matthew Meyerson, M. Cleary. Cell, 2005

659 citations recorded by the source corpus.

Subfields: Hematology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/cd79b632a50f68bbc7abd9309886224271ba2a0d

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Hematology

1. James E. Bradner
2. Scott W. Lowe
3. Richard A. Young

In Molecular Biology

1. James E. Bradner
2. Alexander J. Ruthenburg
3. C. D. Allis
4. R. Roeder
5. Scott W. Lowe
6. C. Vakoc
7. Richard A. Young
8. Yi Zhang

Citations in the corpus

• Regulation of MLL1 H3K4 methyltransferase activity by its core components (2006, background): “or recruitment of HMTs to target genes (ASC2 and menin”
• RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia (2011, background): “These included all eight positive-control shRNAs targeting essential genes ( Rpa1 , Rpa3 , Pcna and Polr2b ), as well as several shRNAs targeting two known MLL-AF9 cofactors ( Men1 and Psip1”