Voltammetric amplified platform based on ionic liquid/NiO nanocomposite for determination of benserazide and levodopa

By M. Miraki, Hassan Karimi-Maleh, M. Taher, Somaye Cheraghi, F. Karimi, Shilpi Agarwal, Vinod Kumar Gupta. Journal of Molecular Liquids, 2019

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Abstract As an electrochemical strategy, we report application of new modified carbon paste electrode amplified with NiO nanoparticle and n-methyl-3-butylimidazolium bromide (CPE/nMBZBr/NiO-NPs) for square wave analysis of benserazide (BZ). The oxidation current of BZ improved ~3.0 times and over-potential of this drug reduces ~50 mV at CPE/nMBZBr/NiO-NPs compare to CPE. Using square wave voltammetric method, we found a relationship between concentration of BZ and oxidation current in the range 20.0 nM–400 μM. The detection limit was calculated ~8.0 nM. In the final step, the CPE/nMBZBr/NiO-NPs resolve overlapping signals BZ and levodopa for simultaneous analysis of these drugs.

Subfields: Biomedical Engineering, Electrical and Electronic Engineering, Electrochemistry

View Paper: https://www.semanticscholar.org/paper/cd6ac424a6950ed747d194778eda53187abbef26