The Vertebrate Primary Cilium in Development, Homeostasis, and Disease
By J. Gerdes, E. Davis, N. Katsanis. Cell, 2009
751 citations recorded by the source corpus.
Cilia are complex structures that have garnered interest because of their roles in vertebrate development and their involvement in human genetic disorders. In contrast to multicellular invertebrates in which cilia are restricted to specific cell types, these organelles are found almost ubiquitously in vertebrate cells, where they serve a diverse set of signaling functions. Here, we highlight properties of vertebrate cilia, with particular emphasis on their relationship with other subcellular structures, and explore the physiological consequences of ciliary dysfunction.
Subfields: Cell Biology, Genetics, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/cd61507ac7169182d00ac960b2036bf595cc569f
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Genetics
Citations in the corpus
- Ciliopathies: an expanding disease spectrum (2011, background): “dation and IFT have been postulated as potential mechanisms [129, 130].”
- Photoreceptor degeneration: genetic and mechanistic dissection of a complex trait (2010, neutral): “Many ciliary proteins are also expressed in other cellular compartments and in non-ocular cells, which accounts for the non-ocular features of many ciliopathies that include R”