Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer.

By Jenny C. Chang, Eric C. Wooten, A. Tsimelzon, S. Hilsenbeck, M. Gutiérrez, R. Elledge, S. Mohsin, C. Osborne, G. Chamness, D. Allred and 1 more. The Lancet, 2003

854 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/cce5f277ab6fed219845f56fe5fa55e6b144a583

How researchers see this paper

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In Cancer Research

1. Tero Aittokallio
2. Mehreen Ali

In Molecular Biology

1. Paul Geeleher
2. Nancy J. Cox
3. Y. Pawitan
4. R. Huang
5. Tero Aittokallio
6. Mehreen Ali

Citations in the corpus

• Effect of separate sampling on classification accuracy (2014, neutral): “Numbering Article Classification problem/source of data 1 [1] Ovarian 2 [10] SRBCT 3 [20] Prediction of outcome in pediatric ALL 4 [15] DLBCL outcome prediction 5 [17] Breast cancer classification 6 [19] Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas 7 [3] Prediction of t”
• Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts (2005, background): “Most microarray studies so far reported have utilized highly selected patient populations [11-13] and hereditary breast cancer [14], and few studies have focused on treatment prediction [15].”
• Deriving chemosensitivity from cell lines: Forensic bioinformatics and reproducible research in high-throughput biology (2009, neutral): “The table does not include 14 outliers in the initial signature for docetaxel that are also found in the list reported by Chang et al. (2003) as being effective separators in the docetaxel test set U95Av2 PS Docetaxel Paclitaxel Doxorubicin U133A PS Cisplatin 114_r_at 1258_s_at 1802_s_at 1847_s_at…”
• Clinical drug response can be predicted using baseline gene expression levels and in vitro drug sensitivity in cell lines (2014, methodology): “To our knowledge, there are four existing datasets that fulfill these criteria [17-20] and the results of our analysis of these data are presented below.”