PubMed related articles: a probabilistic topic-based model for content similarity

By Bmc Bioinformatics, Jimmy J. Lin, J. Wilbur, John Wilbur, Email. 2007

276 citations recorded by the source corpus.

BackgroundWe present a probabilistic topic-based model for content similarity called pmra that underlies the related article search feature in PubMed. Whether or not a document is about a particular topic is computed from term frequencies, modeled as Poisson distributions. Unlike previous probabilistic retrieval models, we do not attempt to estimate relevance–but rather our focus is "relatedness", the probability that a user would want to examine a particular document given known interest in another. We also describe a novel technique for estimating parameters that does not require human relevance judgments; instead, the process is based on the existence of MeSH ® in MEDLINE ®.ResultsThe pmra retrieval model was compared against bm25, a competitive probabilistic model that shares theoretical similarities. Experiments using the test collection from the TREC 2005 genomics track shows a small but statistically significant improvement of pmra over bm25 in terms of precision.ConclusionOur experiments suggest that the pmra model provides an effective ranking algorithm for related article search.

Subfields: General Health Professions, Information Systems, Molecular Biology

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In General Health Professions

  1. Matthew J. Page
  2. Zhiyong Lu
  3. David Moher
  4. M. Rethlefsen
  5. Douglas G. Altman
  6. K. F. Schulz

In Information Systems

  1. Zhiyong Lu

In Molecular Biology

  1. Zhiyong Lu
  2. Robert Leaman
  3. Chih-Hsuan Wei
  4. Thomas C. Wiegers
  5. Carolyn J. Mattingly
  6. Allan Peter Davis
  7. Jiao Li
  8. Daniela Sciaky

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