The organization of the stress system and its dysregulation in depressive illness

By P. Gold. Molecular Psychiatry, 2014

616 citations recorded by the source corpus.

Subfields: Education

View Paper: https://www.semanticscholar.org/paper/cac9d6faf622db501f11d940c1e986fde53cd3db

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In Education

1. K. Ebner
2. Nicolas Singewald

Citations in the corpus

• Stress and neuroinflammation: a systematic review of the effects of stress on microglia and the implications for mental illness (2016, background): “Similarly, the prefrontal cortex has a high number of glucocorticoid binding sites and has been implicated in the body’s response to stress-signalling via mediation of the hypothalamic-pituitary adrenal (HPA) axis (Gold 2015; Diorio et al. 1993).”
• Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus (2016, background): “Depression may disrupt HPA axis, thereby increasing levels of cortisol, catecholamines and inflammatory cytokines, potentially even in a sex-specific manner (251, 252).”
• Peripheral cytokine and chemokine alterations in depression: a meta‐analysis of 82 studies (2017, background): “It has been postulated that melancholic depression is associated with an overactive HPA axis and possibly lower inflammation due to the modulatory effects of cortisol (15, 71).”
• Depression and obesity: evidence of shared biological mechanisms (2018, background): “A comprehensive overview of the research on these clinical subtypes has been previously published in the Mol Psychiatry journal [20].”
• Individual differences in stress susceptibility and stress inhibitory mechanisms (2017, positive): “Indeed, individuals that display particular behavioral and physiological stress-related characteristics due to genetic and epigenetic alterations and are termed susceptible/ vulnerable (Figure 1) have been found to be affected by certain stress-related diseases [2,3], while resilience mechanisms pro”