Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism

By Aurélien Trompette, E. Gollwitzer, C. Pattaroni, Isabel C. Lopez-Mejia, Erika Riva, J. Pernot, N. Ubags, L. Fajas, L. Nicod, B. Marsland. Immunity, 2018

603 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/c9d29ae1ad02afaaec7406549a9273e0e8f290d8

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Citations in the corpus

• Strengthening the Immune System and Reducing Inflammation and Oxidative Stress through Diet and Nutrition: Considerations during the COVID-19 Crisis (2020, background): “Recently, it was shown that mice fed dietary fiber exhibited increased survival rates to influenza virus infection [86] by increasing macrophages with a reduced production of the chemokine CXCL1 (causing neutrophil recruitment to the lung), as well as improving CD8+ T cell function.”
• The Gut-Lung Axis in Health and Respiratory Diseases: A Place for Inter-Organ and Inter-Kingdom Crosstalks (2020, background): “In parallel, diet-derived SCFAs boost CD8+ T-cell effector function in HFD-fed mice (Trompette et al., 2018).”
• Microbes, metabolites, and the gut–lung axis (2019, background): “During influenza infection, SCFAs only influenced the MDP subsets, while other hematopoietic progenitors were unaffected.(111) MDPs commit into either CDPs or monocytes, the latter consisting of two subsets distinguished by Ly6C (also referred to as Gr-1) expression.”