Microglia in Physiology and Disease.

By S. Wolf, H. Boddeke, Helmut Kettenmann. Annual Review of Physiology, 2017

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Multi-sensory gamma stimulation ameliorates Alzheimer’s-associated pathology and improves cognition. (2019, background): “Microglia display an array of responses, ranging from neurotoxic inflammation to phagocytic to neuroprotective, and their dysfunction is known in AD (Heneka et al., 2014; Wolf et al., 2017).”
Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets (2023, methodology): “7 Another approach involved using CD11b + CD45 high and CD11b + CD45 low as markers for peripheral monocytes/macrophages and microglia, respectively 75 and found that during the early stages after focal transient ischemia, microglia exhibit a highly branched morphology and show a faint staining…”
Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner (2017, positive): “…microglia regulate synaptic transmission, synaptic pruning and formation, cell death and survival, as well as embryonic wiring (Hong et al., 2016; Ransohoff and El Khoury, 2015; Reemst et al., 2016; Schafer and Stevens, 2015; Tay et al., 2017b; Thion and Garel, 2017; Volk, 2017; Wolf et al., 2017).”