Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy.

By G. Onder, G. Rezza, S. Brusaferro. Journal of the American Medical Association (JAMA), 2020

4,030 citations recorded by the source corpus.

Only 3 cases of coronavirus disease 2019 (COVID-19) were identified in Italy in the first half of February 2020 and all involved people who had recently traveled to China. On February 20, 2020, a severe case of pneumonia due to SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) was diagnosed in northern Italy’s Lombardy region in a man in his 30s who had no history of possible exposure abroad. Within 14 days, many other cases of COVID-19 in the surrounding area were diagnosed, including a substantial number of critically ill patients.1 On the basis of the number of cases and of the advanced stage of the disease it was hypothesized that the virus had been circulating within the population since January. Another cluster of patients with COVID-19 was simultaneously identified in Veneto, which borders Lombardy. Since then, the number of cases identified in Italy has rapidly increased, mainly in northern Italy, but all regions of the country have reported having patients with COVID-19. After China, Italy now has the second largest number of COVID-19 cases2 and also has a very high case-fatality rate.3 This Viewpoint reviews the Italian experience with COVID-19 with an emphasis on fatalities.

Subfields: Oncology

View Paper: https://www.semanticscholar.org/paper/c952098c9f149d4a4482e8fbcc0c5d3bbe800c0e

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Citations in the corpus

A cross-country database of COVID-19 testing (2020, methodology): “Methods The database consists of two parts, provided for each included country: (1) a time series for the cumulative and daily number of tests performed, or people tested, plus derived variables (discussed below); (2) metadata including a detailed description of the source and any available informat”
A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID‐19) Pandemic: An International Collaborative Group (2020, methodology): “Adapted from [19] with permission from The European Society for Blood and Marrow Transplantation.”
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COVID-19 pathophysiology: A review (2020, neutral): “2% [15,18], which was three times as high as the one in China.”
Diabetes in COVID-19: Prevalence, pathophysiology, prognosis and practical considerations (2020, background): “found diabetes in nearly 36%, while CVD was associated in nearly 43% of 355 patients admitted with COVID-19 [12].”
Exposure to air pollution and COVID-19 mortality in the United States: A nationwide cross-sectional study (2020, methodology): “Acknowledgments: The computations in this paper were run on (1) the Odyssey cluster supported by the FAS Division of Science, Research Computing Group at Harvard University; and (2) the”
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