Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans

By N. Pellegata, L. Quintanilla‐Martinez, H. Siggelkow, Elenore Samson, K. Bink, H. Höfler, F. Fend, J. Graw, M. Atkinson. Proceedings of the National Academy of Sciences of the United States of America, 2006

620 citations recorded by the source corpus.

Subfields: Epidemiology, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/c8df31e754375e5548832cbcdb5892e8ca181a03

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In Molecular Biology

1. J. M. Roberts
2. S. Dowdy
3. A. Besson

In Oncology

1. J. M. Roberts
2. S. Dowdy
3. A. Besson

Citations in the corpus

• CDK inhibitors: cell cycle regulators and beyond. (2008, positive): “…endocrine neoplasia (MEN) was linked to a germline nonsense mutation in the cdkn1b gene, and germline mutations in the human cdkn1b gene are also associated with MEN (Georgitsi et al., 2007; Pellegata et al., 2006). p27 expression is a prognostic marker for clinical outcome in human cancers.”