Measures of bioavailable serum testosterone and estradiol and their relationships with muscle strength, bone density, and body composition in elderly men.

By A. V. D. Beld, F. Jong, Diederick E. Grobbee, H. Pols, S. Lamberts. Journal of Clinical Endocrinology and Metabolism, 2000

643 citations recorded by the source corpus.

Subfields: Cell Biology, Endocrinology, Diabetes and Metabolism

View Paper: https://www.semanticscholar.org/paper/c799bca2b236aa831fe0f62fa866d7a084bd0401

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Citations in the corpus

Prevalence of sarcopenia and predictors of skeletal muscle mass in healthy, older men and women. (2002, background): “Bioavailable testosterone is related to lower extremity strength and function (41,42), and testosterone treatment in older hypogonadal men increased hand-grip strength (43,44) and lower extremity muscle strength (13,45).”
Hypothalamic-pituitary-testicular axis disruptions in older men are differentially linked to age and modifiable risk factors: the European Male Aging Study. (2008, result): “The present study confirms the age-related cross-sectional trendsincirculatingTincommunity-dwellingmen(6).Themagnitude of fall in total T is modest (0.4% per annum); this is similartosome(16, 17 )butlessthanthatofothercross-sectional studies typically reporting a 0.4–2% annual decline (18–20).”
Irisin is expressed and produced by human muscle and adipose tissue in association with obesity and insulin resistance. (2013, background): “These different associations could be interpreted in the context of the well-known inverse associations between muscle mass and fat mass or BMI in men (22).”
Satellite cells and the muscle stem cell niche. (2013, background): “During aging, systemic levels of androgens decline, which is concomitant with a loss in muscle mass and a gain in fat mass (228, 544).”
The decline of androgen levels in elderly men and its clinical and therapeutic implications. (2005, background): “As a consequence of the age-associated increase in SHBG binding capacity, the serum concentrations of free estradiol and non-SHBG-bound or “bioavailable” estradiol do show a moderate age-associated decrease (36, 71, 72) (Fig.”