Target-oriented and diversity-oriented organic synthesis in drug discovery.

By Stefan Schreiber. Science, 2000

2,076 citations recorded by the source corpus.

Subfields: Molecular Biology, Organic Chemistry, Pharmacology

View Paper: https://www.semanticscholar.org/paper/c743cced47081bead7feccd35aee462cd3f9f5b2

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Ralph Weissleder
2. E. Sun
3. Christopher M. Dobson
4. Gisbert Schneider
5. J. Kinet
6. C. Walsh
7. S. Garman
8. P. Colman

In Organic Chemistry

1. Gisbert Schneider
2. Christopher M. Dobson
3. J. Kinet
4. C. Walsh
5. S. Garman
6. P. Colman
7. G. Fu
8. Junwon Choi

In Pharmacology

1. Christopher M. Dobson
2. Gisbert Schneider
3. J. Kinet
4. C. Walsh
5. S. Garman
6. P. Colman
7. G. Fu
8. Junwon Choi

Citations in the corpus

• Automating drug discovery (2017, background): “For example, diversity-oriented synthesis (DOS) provides a rationale for generating collections of small molecules with diverse functional groups, stereochemistry and frameworks in a controlled fashion 15,16 .”
• Opinion — anti-infectives: Where will new antibiotics come from? (2003, background): “Several efforts to produce libraries in accordance with such criteria have recently been reported and reviewe”
• Chemical space and biology (2004, background): “Now, with the immense developments in combinatorial methods over the past decade or so, huge arrays of new molecules can be produced in relatively short periods of tim”