Persistent bacterial infections and persister cells

By Robert A. Fisher, Bridget Gollan, S. Helaine. Nature Reviews Microbiology, 2017

1,086 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Prevalence and Therapies of Antibiotic-Resistance in Staphylococcus aureus (2020, background): “The presence of persister cells poses many obstacles to the complete elimination of bacterial infections and the prevention of recurrent infections (Fisher et al., 2017; Foster, 2017).”
Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics (2022, background): “Persistent molecules from the persisters can maintain vitality and refill biofilms; once antibiotics are not present, bacteria will resume growth and cause chronic infections.(264) Altogether, P.”
Antibiotic resistance and persistence—Implications for human health and treatment perspectives (2020, positive): “Persistent infections are also known as chronic infections and are often associated with antibiotic treat-ment failure (Rhen et al , 2003; Fisher et al , 2017).”
Liquid-Liquid Phase Separation in Disease. (2019, background): “One problem with treating bacterial and fungal infections is the presence of persisting or dormant cells that are resistant to treatment with cytostatic drugs (51).”