Escaping the nuclear confines: signal-dependent pre-mRNA splicing in anucleate platelets.

By M. Denis, N. Tolley, M. Bunting, H. Schwertz, Huimiao Jiang, S. Lindemann, C. C. Yost, F. Rubner, K. Albertine, K. Swoboda and 6 more. Cell, 2005

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Platelets and the immune continuum (2011, background): “Furthermore, platelets contain all the translational machinery necessary to generate their own proteins during haemostatic and inflammatory event”
RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics (2015, neutral): “We observed strong negative correlations with RNAs implicated in RNA translation, T cell immunity, and inter-leukin-signaling, implying diminished needs of TEPs for RNAs involved in these biological processes or orchestrated translation of these RNAs to proteins (Denis et al., 2005).”
Circulating Platelets as Mediators of Immunity, Inflammation and Thrombosis (2018, background): “In addition to surface protein expression, platelets can synthesize proteins from stored RNA templates.(46,47) One of these proteins, the cytokine IL-1β, is synthesized in response to inflammatory stimuli(46) (Figure 2).”