What turns CREB on?

By M. Johannessen, M. Delghandi, U. Moens. Cellular Signalling, 2004

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ERK1/2 MAP kinases in cell survival and apoptosis (2006, background): “ERK-activated RSK phosphorylates the transcription factor cAMP response element-binding protein (CREB) at serine 133 ( 61 ), which allows recruitment of the co-activators CREB-binding protein (CBP) and p300 and strongly enhances CREB-dependent transcription ( 76 ).”
Hydrogen peroxide sensing, signaling and regulation of transcription factors (2014, background): “More than 20 different protein kinases, members of distinct signaling pathways, have been described as CREB kinases [95][97].”
CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer (2010, background): “Stimuli involved in the PKA pathway that can induce phosphorylation of CREB have been excellently reviewed elsewhere (44).”
Importin α transports CaMKIV to the nucleus without utilizing importin β (2005, background): “In many cases, it has been shown that CaMKIV functions as a nuclear kinase whose principal substrate is CREB, a transcriptional focal point of numerous cellular signaling pathways (for reviews, see Shaywitz and Greenberg, 1999; Johannessen et al, 2004).”
Transcription Factors in Long-Term Memory and Synaptic Plasticity (2009, positive): “CBP and p300 are transcription coactivators with intrinsic histone acetyltransferase activity, which is necessary for mediating transcription enhancement (107, 112).”