Embolic strokes of undetermined source: the case for a new clinical construct.

By R. Hart, H. Diener, S. Coutts, J. Easton, C. Granger, M. O’Donnell, R. Sacco, S. Connolly. Lancet Neurology, 2014

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Antithrombotic Therapy for Atrial Fibrillation: CHEST Guideline and Expert Panel Report (2012, background): “ESUS has been defined as ischemic stroke detected by CT or MRI that, after a standardized and adequate diagnostic pathway including brain imaging, echocardiography, cardiac rhythm monitoring for at least 24 h, and imaging of the intracranial and extracranial arteries supplying the affected brain are”
SARS2-CoV-2 and Stroke in a New York Healthcare System (2020, background): “In patients with COVID-19 requiring invasive respiratory support, the median duration of mechanical ventilation has been reported 11 days,8 which renders them vulnerable to complications associated with critical illness and a prolonged intensive care unit stay including the risk for (1) hypotension ”
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. (2016, neutral): “A broader definition is embolic stroke of undetermined source.(154) Several studies have also found AF in patients in whom another competing cause for stroke has been”