Application of heat shock protein expression for detecting natural adaptation and exposure to stress in natural populations
By J. G. Sørensen. 2010
106 citations recorded by the source corpus.
Heat-shock proteins (HSPs) play an undisputed role for maintaining cellular functioning under environmental chal- lenges and protein denaturing conditions. Compelling evidence points to an evolutionary important role of HSPs and a strict evo- lutionary control of these proteins as a balance between benefits and costs. While there is a great potential for using HSP expres- sion for detecting natural adaptation and exposure to stress in natural populations, some obstacles and key issues await investiga- tion. From an ecological perspective these key issues needs to be resolved in order to fully appreciate the complex responses and adaptations to stress and to increase our understanding of HSPs and other molecular chaperones for stress adaptation and potential use as biomarkers. Here, the current knowledge and understanding of HSPs is reviewed and a number of key issues including the interpretation of elevated HSP levels, the complications of extrapolating between laboratory and field conditions, the effects of choice of traits and methodology and the larger intra-and extracellular networks of interactions that HSPs participate in are dis- cussed (Current Zoology 56 (6): 703-713, 2010).
Subfields: Ecology, Molecular Biology, Physical and Theoretical Chemistry
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In Ecology
Citations in the corpus
- The use of fluctuating asymmetry as a measure of environmentally induced developmental instability: A meta-analysis (2013, background): “In the case of heat shock proteins, technical issues such as the availability of antibodies for specific species limits the use of these stress proteins for environmental assessment (Sørensen, 2010).”