Bile acid is a host factor that regulates the composition of the cecal microbiota in rats.

By K. Islam, S. Fukiya, Masahito Hagio, N. Fujii, S. Ishizuka, Tadasuke Ooka, Yoshitoshi Ogura, Tetsuya Hayashi, A. Yokota. Gastroenterology, 2011

857 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/c42ef2c1de9b40ff1dc8808098ebe01ad425f78b

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Citations in the corpus

Modulation of the Fecal Bile Acid Profile by Gut Microbiota in Cirrhosis (2013, positive): “The gut milieu in cirrhosis involves the interaction between the microbiota and secreted factors, such as bile acids (BAs) that can also modulate the gut barrier [4].”
The composition of the gut microbiota shapes the colon mucus barrier (2014, positive): “Our study corroborates previous studies showing an association between altered diets and an increase in Erysipelotrichi and Allobaculum, but various effects are shown for fat-enriched diets [29–32].”
Hepatic inflammatory responses in liver fibrosis (2023, positive): “If fewer primary bile acids reach the small intestine, pro-inflammatory bacteria overgrow other species, and the associated increase in toxic bile acids exacerbates liver cell damage and inflammation 33 .”
Mechanisms and consequences of intestinal dysbiosis (2017, background): “1 3 rats with cholic acid leads to a microbial composition resembling the obesity pattern of low Bacteroidetes to Firmicutes ratio [48].”
Bile Acids and the Gut Microbiome (2014, background): “3% in control rats to between 55 and 62% when the mice were fed cholic acid [12].”
Altered Bile Acid Profile Associates with Cognitive Impairment in Alzheimer’s Disease – An Emerging Role for Gut Microbiome (2018, positive): “BAs also modulate the gut microbiome [22,23] and seem to be indicators of gut dysbiosis.”
Gut Microbiota in Cardiovascular Health and Disease (2017, background): “BAs have also been described to affect the cecal microbiota composition of rats, and a direct antimicrobial effect of BAs has been described in vitro.(115,116) Thus, a reciprocal and complex inter-relationship exists between gut microbial metabolism of BAs, and BAs affect microbial composition and f”
Bile Acid Signaling in Metabolic Disease and Drug Therapy (2014, background): “Feeding rats with a CA-containing diet resulted in increased gut Firmicutes-to-Bacteroidetes ratio, which was also seen in obese mice (Islam et al., 2011).”
Effect of dietary bile acids on growth, body composition, lipid metabolism and microbiota in grass carp (Ctenopharyngodon idella) (2018, background): “…that indicated that BA affected growth and diversity of microbiota in the intestine (Bajor, Gillberg, & Abrahamsson, 2010; D’Aldebert et al., 2009; Islam et al., 2011; Kurdi, Kawanishi, Mizutani, & Yokota, 2006), as members of the microbiome utilize bile acids and their conjugates (Ridlon, Kang,…”