Highly sensitive graphene biosensors based on surface plasmon resonance.

By Lin Wu, H. Chu, Wee Shing Koh, E. Li. Optics Express, 2010

865 citations recorded by the source corpus.

A surface plasmon resonance (SPR) based graphene biosensor is presented. It consists of a graphene sheet coated above a gold thin film, which has been proposed and experimentally fabricated recently [ChemPhysChem 11, 585 (2010)]. The biosensor uses attenuated total reflection (ATR) method to detect the refractive index change near the sensor surface, which is due to the adsorption of biomolecules. Our calculations show that the proposed graphene-on-gold SPR biosensor (with L graphene layers) is (1 + 0.025 L) x gamma (where gamma > 1) times more sensitive than the conventional gold thin film SPR biosensor. The improved sensitivity is due to increased adsorption of biomolecules on graphene (represented by the factor gamma) and the optical property of graphene.

Subfields: Biomedical Engineering, Electrical and Electronic Engineering, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/7e4117ee2f05b6c549874c91eea459a4bbd7f714

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Citations in the corpus

Recent advances in surface plasmon resonance imaging: detection speed, sensitivity, and portability (2017, positive): “have shown that a thin layer of graphene covering the gold thin film in a conventional SPR sensor would improve the sensitivity due to the increased adsorption of biomolecules on graphene and the optical property of graphene [80].”
Sensitivity Improved SPR Biosensor Based on the MoS2/Graphene–Aluminum Hybrid Structure (2017, methodology): “005 [21], [36].”