Identification of a cis‐acting element required for dendritic targeting of activity‐regulated cytoskeleton‐associated protein mRNA

By Hiroaki Kobayashi, Sachiya Yamamoto, T. Maruo, F. Murakami. 2005

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BDNF-induced local protein synthesis and synaptic plasticity. (2014, unknown): “Similarly, two different localization elements were described for the Arc mRNA (Gao et al., 2008; Kobayashi et al., 2005) but surprisingly little is known about the mechanism of Arc mRNA transport into dendrites.”
Permanent Genetic Access to Transiently Active Neurons via TRAP: Targeted Recombination in Active Populations (2013, background): “…strategy displaced the introns, coding sequences, and endogenous Fos and Arc 3'UTRs, which are known to contain elements important for mRNA degradation and dendritic localization (Giorgi et al., 2007; Kobayashi et al., 2005; Wilson and Treisman, 1988), to the 3' end of the CreER-SV40pA cassette.”