Liver Fluke Induces Cholangiocarcinoma

By B. Sripa, Sasithorn Kaewkes, Paiboon Sithithaworn, Eimorn Mairiang, T. Laha, M. Smout, Chawalit Pairojkul, Vajaraphongsa Bhudhisawasdi, Smarn Tesana, Bandit Thinkamrop and 3 more. PLoS Medicine, 2007

755 citations recorded by the source corpus.

The authors discuss the molecular pathogenesis of opisthorchiasis and associated cholangiocarcinogenesis, particularly nitrative and oxidative DNA damage and the clinical manifestations of cholangiocarcinoma.

Subfields: Parasitology, Small Animals, Surgery

View Paper: https://www.semanticscholar.org/paper/c2da18f01b07367a4c3724e77dc9ca60ead904a2

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Citations in the corpus

• The Role of Cancer-Associated Fibroblasts and Fibrosis in Liver Cancer (2016, background): “PSC encompasses many changes in the PME that may drive cancer development, including increased cholangiocyte proliferation, inflammation, fibrosis, and in advanced stages, cirrhosis (186, 194, 195).”