The SWISS-MODEL Repository: new features and functionalities
By Jürgen Kopp, Torsten Schwede. 2005
436 citations recorded by the source corpus.
The SWISS-MODEL Repository is a database of annotated 3D protein structure models generated by the SWISS-MODEL homology-modelling pipeline. As of September 2005, the repository contained 675 000 models for 604 000 different protein sequences of the UniProt database. Regular updates ensure that the content of the repository reflects the current state of sequence and structure databases, integrating new or modified target sequences, and making use of new template structures. Each Repository entry consists of one or more 3D models accompanied by detailed information about the target protein and the model building process: functional annotation, a detailed template selection log, target-template alignment, summary of the model building and model quality assessment. The SWISS-MODEL Repository is freely accessible at .
Subfields: Materials Chemistry, Molecular Biology
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Materials Chemistry
- Torsten Schwede
- Yang Zhang
- Andrej Sali
- Ben M. Webb
- Lorenza Bordoli
- Andriy Kryshtafovych
- Gaetano T. Montelione
- Krzysztof Fidelis
In Molecular Biology
- Torsten Schwede
- Yang Zhang
- Andrej Sali
- Burkhard Rost
- Andriy Kryshtafovych
- Lorenza Bordoli
- Ben M. Webb
- David T. Jones
Citations in the corpus
- New developments in the InterPro database (2007, methodology): “Proteins with 3D structures modelled by MODBASE (17) and SWISS-MODEL (18) have links to the structure predictions from the match graphical views.”
- A structural biology community assessment of AlphaFold2 applications (2021, methodology): “Regarding coverage, previous attempts to generate ‘proteome-wide’ structural models include those based on homology models, such as the SWISS-MODEL Repository (SMR) 14 , and more recently, the modeling of known protein domains in the Pfam database 15 using trRosetta 16 .”
- The Protein Model Portal (2008, background): “…portal federates protein model data from different providers (CSMP, JCSG, MCSG, NESG, NYSGXRC, JCMM, Mod-Base [10], and SWISS-MODEL Repository [22, 23]) by integrating model meta information: the segment of a target protein for which a model is available, template structure (PDB ID and chain),…”
- Outcome of a workshop on archiving structural models of biological macromolecules. (2006, background): “Other helpful resources are databases of precalculated comparative protein structure models for protein sequences (Kopp and Schwede, 2006; Pieper et al., 2006).”
- The SWISS-MODEL Repository and associated resources (2008, methodology): “We emphasize the improvements of the SWISS-MODEL Repository which have been implemented since our last report (27).”
- InterPro: the integrative protein signature database (2008, methodology): “A new file (feature.xml) has been created which contains non-signature match data from the structural databases (PDB, MODBASE and SWISS-MODEL) for UniProtKB proteins.”