A framework for assessing inter-individual variability in pharmacokinetics using virtual human populations and integrating general knowledge of physical chemistry, biology, anatomy, physiology and…
By Masoud Jamei, G. Dickinson, Amin Rostami-Hodjegan. Drug Metabolism and Pharmacokinetics, 2009
368 citations recorded by the source corpus.
Subfields: Computational Theory and Mathematics, Spectroscopy, Statistics and Probability
View Paper: https://www.semanticscholar.org/paper/c239e065223fe78832ab81f0d45d32c1d1334e71
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In Spectroscopy
In Statistics and Probability
Citations in the corpus
- PBPK models for the prediction of in vivo performance of oral dosage forms. (2014, methodology): “The lengths and radii of intestinal regions are individualized based upon covariation with body surface area and jejunal–ileal ratios, enabling individualized regional absorptive surface areas to be determined (Jamei et al., 2009b).”