Human gut microbiome and risk for colorectal cancer.

By Jiyoung Ahn, R. Sinha, Zhiheng Pei, Christine Dominianni, Jing Wu, Jianxin Shi, J. Goedert, R. Hayes, Liying Yang. Journal of the National Cancer Institute, 2013

891 citations recorded by the source corpus.

Subfields: Molecular Biology, Physiology, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/0d721c2517d11da97bc255fc7b64f53e8c528516

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Citations in the corpus

Fusobacterium nucleatum and T-cells in Colorectal Carcinoma (2015, neutral): “31 Mutant 87 (16) 75 (16) 6 (19) 5 (14)”
Mechanisms and consequences of intestinal dysbiosis (2017, background): “Colorectal cancer is associated with increased abundance of the phyla Firmicutes and Fusobacteria [203, 204].”
Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in mice (2016, result): “This loss of community diversity can be explained by the tumor-induced dysbiosis in the gut bacteria community, consistent with previous findings that some diseases could lead to an imbalanced gut microbiota and decrease the ecological diversity in the gut (21, 22).”
Gastric microbial community profiling reveals a dysbiotic cancer-associated microbiota (2017, background): “31 33 34 For example, patients with colorectal cancer had decreased overall microbial community diversity in comparison to healthy controls.”
Identifying Keystone Species in the Human Gut Microbiome from Metagenomic Timeseries Using Sparse Linear Regression (2014, background): “Abundance of both Bacteroides fragilis and Bacteroides stercosis are associated with an increased risk of colon cancer [5,6,10], and previous authors even suggest that Bacteroides fragilis acts as a critical ‘‘keystone pathogen’’ in the development of the disease [8].”