Induction and suppression of RNA silencing: insights from viral infections

By Olivier Voinnet. Nature reviews genetics, 2005

870 citations recorded by the source corpus.

Subfields: Animal Science and Zoology, Cardiology and Cardiovascular Medicine, Plant Science

View Paper: https://www.semanticscholar.org/paper/c1d519a8d8daad2710c6c3dabe544ad36e8db8e3

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Animal Science and Zoology

In Cardiology and Cardiovascular Medicine

In Plant Science

Citations in the corpus

RNA silencing: Methods and protocols (2006, neutral): “Specific circulating miRNA profiles have previously been described in patients with chronic heart failure (CHF).[5-9] A few studies have examined miRNAs in acute heart failure (AHF).”
RNA virus interference via CRISPR/Cas13a system in plants (2017, background): “Despite the promising potential of these transgenic approaches, many drawbacks have limited their applications in agriculture [27-29].”
Gene silencing in plants using artificial microRNAs and other small RNAs. (2008, background): “Not surprisingly, many viruses encode so-called viral suppressor proteins, which counteract the silencing of viral genomes by DCL and Argonaute proteins (Voinnet, 2005b).”
Management of Virus and Viroid Diseases of Crops in the Tropics (2014, background): “PTGS as a defense mechanism against viruses in plants is mediated by virus-derived small interfering RNAs from 21 to 24 nucleotides long (Baulcombe 2005; Meister and Tsuchl 2004; Voinnet 2005).”
Highly Specific Gene Silencing by Artificial MicroRNAs in Arabidopsis[W][OA] (2006, background): “These extend the local RNA double strands and generate templates for production of secondary siRNAs by Dicer action (Voinnet, 2005).”
Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense. (2006, background): “In addition, VIGS may also generate a mobile silencing signal that primes RNA silencing in uninfected cells (Baulcombe 2004; Voinnet 2005).”
A MicroRNA Superfamily Regulates Nucleotide Binding Site–Leucine-Rich Repeats and Other mRNAs[W][OA] (2012, background): “The viral suppressors are a counterdefense system (Voinnet, 2005), and miR482 is then a counter-counterdefense system that is dependent on the counterdefense system.”
The RNA silencing endonuclease Argonaute 2 mediates specific antiviral immunity in Drosophila melanogaster. (2006, background): “Given that the RNA silencing pathway plays a critical role in antiviral defense in plants (Baulcombe 2004; Voinnet 2005), it has been hypothesized that the RNAi cleavage pathway of animals also provides a defense mechanism against parasitic nucleic acids, such as viruses and transposons.”