Early versus delayed invasive intervention in acute coronary syndromes.

By S. Mehta, C. Granger, W. Boden, P. Steg, J. Bassand, D. Faxon, Rizwan Afzal, S. Chrolavicius, S. Jolly, P. Widimsky and 8 more. New England Journal of Medicine, 2009

875 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Radiology, Nuclear Medicine and Imaging, Surgery

View Paper: https://www.semanticscholar.org/paper/c1cb0082001c922c7dac244a61d0ab9ae70f5f2e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cardiology and Cardiovascular Medicine

1. Hani Jneid
2. Judith Hochman
3. Allan S. Jaffe
4. Georgia Salanti

In Surgery

1. Georgia Salanti
2. A. Liberati
3. Judith Hochman

Citations in the corpus

• 2009 Focused Updates: ACC/AHA Guidelines for the Management of Patients With ST‐Elevation Myocardial Infarction (Updating the 2004 Guideline and 2007 Focused Update) and ACC/AHA/SCAI Guidelines on Percutaneous Coronary Intervention (Updating the 2005 Guideline and 2007 Focused Update) (2009, methodology): “Overall in TIMACS, early intervention trended to be superior to delayed intervention in preventing the composite of death, MI, or stroke (primary end point), but the difference was not statistically significant.(23) However, early intervention reduced the composite of death, MI, or refractory ischem”
• 2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. (2014, methodology): “Similarly, the GRACE risk model can identify patients who would benefit from an early invasive strategy.(139) Patients with elevated cardiac troponin benefit from more aggressive therapy, whereas those without elevated cardiac troponins may not.”
• Guidelines on myocardial revascularization. (2010, background): “In high-risk patients with a GRACE risk score >140, urgent angiography should be performed within 24 h if possible [66].”
• 2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. (2014, methodology): “Patients already taking daily aspirin before PCI should take 81 mg to 325 mg non–enteric-coated aspirin before PCI (27, 190-192).”
• Timing Matters in Hip Fracture Surgery: Patients Operated within 48 Hours Have Better Outcomes. A Meta-Analysis and Meta-Regression of over 190,000 Patients (2012, background): “This approach is generally accepted in cardiology where there are several examples of randomized trials evaluating the optimal timing of invasive interventions [61,62].”