Xenobiotic-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons.

By T. Shimada. Drug Metabolism and Pharmacokinetics, 2006

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Microbial biodegradation of polyaromatic hydrocarbons. (2008, background): “It was well known that mammalian P450 plays key roles not only in the detoxification of PAHs but also in the activation of PAHs (Shimada, 2006).”