Purinergic Signaling during Inflammation
By H. Eltzschig, M. Sitkovsky, S. Robson. New England Journal of Medicine, 2012
709 citations recorded by the source corpus.
Receptors for ATP and ADP and adenosine exert various effects. ATP and ADP signaling is mainly proinflammatory, and adenosine signaling is mainly antiinflammatory. Receptors for these nucleosides are emerging as therapeutic targets in a number of inflammatory and autoimmune diseases.
Subfields: Neurology, Physiology
View Paper: https://www.semanticscholar.org/paper/c0cdef105f057d8d3fcae9b6ef6766c9f1e45d7b
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In Physiology
Citations in the corpus
- Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper (2015, background): “flammatory processes, which can be suppressed by the inhibition of the purinergic signalling pathway (212,213).”