Rethinking schizophrenia

By Thomas R. Insel. Nature, 2010

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Critical periods in speech perception: new directions. (2015, background): “Notably, many mental illnesses that include language impairment—such as schizophrenia and autism—are of neurodevelopmental origin and share defects in the triggers and brakes that normally regulate CP timing (Gogolla et al. 2009, Insel 2010, Rubenstein & Merzenich 2003).”
Definition and description of schizophrenia in the DSM-5. (2013, background): “The validity of our construct of schizophrenia has, however, been increasingly drawn into question (Hyman, 2010; Insel, 2010).”
The Philadelphia Neurodevelopmental Cohort: A Publicly Available Resource for the Study of Normal and Abnormal Brain Development in Youth (2015, positive): “The PNC is a resource that responds to a paradigm shift in the field of psychiatric neuroscience, where major mental illnesses are increasingly conceptualized as disorders of development (Insel, 2010; Insel, 2009; Casey et al., 2014; Paus et al., 2008).”
Enhancing visual working memory in schizophrenia: effects of frontoparietal theta tACS in low-performing patients (2024, background): “Schizophrenia (SCZ) is a debilitating neuropsychiatric disorder that affects between 0.4% and 1% of the global population 1 .”