Interpreting Diagnostic Tests for SARS-CoV-2.

By N. Sethuraman, S. S. Jeremiah, A. Ryo. Journal of the American Medical Association (JAMA), 2020

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The pandemic of coronavirus disease 2019 (COVID-19) continues to affect much of the world. Knowledge of diagnostic tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still evolving, and a clear understanding of the nature of the tests and interpretation of their findings is important. This Viewpoint describes how to interpret 2 types of diagnostic tests commonly in use for SARS-CoV-2 infections—reverse transcriptase–polymerase chain reaction (RT-PCR) and IgM and IgG enzyme-linked immunosorbent assay (ELISA)—and how the results may vary over time (Figure).

Subfields: Infectious Diseases

View Paper: https://www.semanticscholar.org/paper/c013a8d328b8aa32aaf87f197aa7f1aee1d9da18