Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA
By Paul G. Mullins, David J McGonigle, R. O. Tuura, Nicolaas A. J. Puts, Rishma Vidyasagar, C. John Evans, Richard A. E. Edden. NeuroImage, 2012
561 citations recorded by the source corpus.
There is increasing interest in the use of edited proton magnetic resonance spectroscopy for the detection of GABA in the human brain. At a recent meeting held at Cardiff University, a number of spectroscopy groups met to discuss the acquisition, analysis and interpretation of GABA-edited MR spectra. This paper aims to set out the issues discussed at this meeting, reporting areas of consensus around parameters and procedures in the field and highlighting those areas where differences remain. It is hoped that this paper can fulfill two needs, providing a summary of the current ‘state-of-the-art’ in the field of GABA-edited MRS at 3 T using MEGA-PRESS and a basic guide to help researchers new to the field to avoid some of the pitfalls inherent in the acquisition and processing of edited MRS for GABA.
Subfields: Cognitive Neuroscience, Radiology, Nuclear Medicine and Imaging, Spectroscopy
View Paper: https://www.semanticscholar.org/paper/bf670a971ed85f48f976ec18af91524cb7096403
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In Radiology, Nuclear Medicine and Imaging
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Citations in the corpus
- Gannet: A Batch-Processing Tool for the Quantitative Analysis of Gamma-Aminobutyric Acid–Edited MR Spectroscopy Spectra (2013, methodology): “It is possible to noninvasively detect GABA using in vivo magnetic resonance spectroscopy (MRS) (1,2), and this has been used to investigate the role of GABA in healthy brain function (3–5) and pathological changes in GABA concentration in a range of neurological (6–8), psychiatric (9–15), and devel”