Adherence to bisphosphonate therapy and fracture rates in osteoporotic women: relationship to vertebral and nonvertebral fractures from 2 US claims databases.

By E. Siris, S. T. Harris, C. Rosen, C. Barr, J. N. Arvesen, T. Abbott, S. Silverman. Mayo Clinic proceedings, 2006

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Bisphosphonates: Mechanism of Action and Role in Clinical Practice (2008, unknown): “19,20 Accordingly, studies examining bisphosphonate therapy adherence suggest that, by addressing patient concerns of medication safety and timing, clinicians can significantly improve adherence.”
Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: a need for international reference standards (2011, background): “There is some evidence that the response to treatment is suboptimal in those who adhere poorly [141, 142].”