Axcaliber: A method for measuring axon diameter distribution from diffusion MRI

By Yaniv Assaf, T. Blumenfeld-Katzir, Yossi Yovel, Peter J. Basser. Magnetic Resonance in Medicine, 2008

928 citations recorded by the source corpus.

Subfields: Orthopedics and Sports Medicine, Public Health, Environmental and Occupational Health, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/be6afdaa72fb2248f3c2c95981cf3714268d06de

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In Orthopedics and Sports Medicine

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Citations in the corpus

Neurite density from magnetic resonance diffusion measurements at ultrahigh field: Comparison with light microscopy and electron microscopy (2009, neutral): “Assaf et al. (2008) accomplished good agreement between histological measurements of axonal diameter distributions and diffusion MRI by utilizing their modeling framework " AxCaliber.”
Diffusion MRI at 25: Exploring brain tissue structure and function (2012, background): “…diffusion behavior and diffusion anisotropy in white matter, with the potential to estimate white matter fiber average diameter (Assaf et al., 2008), it remains to be seen how it could be applied to the brain cortex, given that true restricted diffusion effects have not been…”
In vivo histology of the myelin g-ratio with magnetic resonance imaging (2015, methodology): “Combinedwithmeasurement of the axon diameter distribution, which is possible with techniques such as “AxCaliber” (Assaf et al., 2008) and “ActiveAx” (Zhang et al., 2011), the g-ratio will allow us to see a more complete picture of white matter microstructure from imaging data.”
The Human Connectome Project and Beyond: Initial Applications of 300 mT/m Gradients (2013, methodology): “Moreover, the benefits of stronger gradients transcend the Human Connectome Project, enabling a much sought-after platform for diffusion imaging methods such as AxCaliber to be applied in the in vivo human brain.”
Investigating white matter fibre density and morphology using fixel-based analysis (2017, methodology): “…in the radial orientation (Alexander, 2008; Assaf and Basser, 2005; Barazany et al., 2009; Jespersen et al., 2007; Lu et al., 2006; Raffelt et al., 2012b; Stanisz et al., 1997; Zhang et al., 2012), and that the exchange of water between the intra-axonal and extra-axonal space is negligible on the…”
NODDI: Practical in vivo neurite orientation dispersion and density imaging of the human brain (2012, background): “Estimating axon diameter, however, has onerous demands for both acquisition and fitting (Alexander et al., 2010; Assaf et al., 2008; Barazany et al., 2009; Zhang et al., 2011).”
Q-space trajectory imaging for multidimensional diffusion MRI of the human brain (2016, positive): “Some of these limitations are specific to DTI and can be resolved by biophysical modeling and measurements with di↵erent di↵usion times [5, 6].”
Accelerated Microstructure Imaging via Convex Optimization (AMICO) from diffusion MRI data (2015, methodology): “The AxCaliber model (Assaf et al., 2008) is an extension of CHARMED in which the axon radii are explicitly modeled using Gamma distributions, rather than being ﬁ xed to a given size.”
White matter integrity, fiber count, and other fallacies: The do's and don'ts of diffusion MRI (2013, neutral): “2004), AxCaliber (Assaf et al., 2008), ActiveAx (Alexander et al.”
Multi-tissue constrained spherical deconvolution for improved analysis of multi-shell diffusion MRI data (2014, neutral): “The average orientation was computed as the mean dyadic tensor of all fODF peaks (Basser and Pajevic, 2000).”
Apparent Fibre Density: A novel measure for the analysis of diffusion-weighted magnetic resonance images (2012, methodology): “The AFD is based on the widely-used assumption that intra-axonal water is restricted in the radial direction (Stanisz et al., Jan., 1997; Alexander, Aug., 2008; Alexander et al., 2010; Assaf and Basser, 2005; Assaf et al., 2008; Barazany et al., May, 2009).”
Dipy, a library for the analysis of diffusion MRI data (2014, neutral): “We have also started looking into tissue characterization in microstructure (Assaf et al., 2008).”
Tractography - where do we go from here? (2011, neutral): “Some of the more complex diffusion modeling such as DSI (Wedeen et al., 2005), micro-structural modeling (Assaf et al., 2008), or models for ﬁber spreading require a large number of data volumes.”
Graph analysis of the human connectome: Promise, progress, and pitfalls (2013, neutral): “, 2010) or diffusion-based estimates of axonal structure (Alexander et al., 2010; Assaf et al., 2008).”
White matter characterization with diffusional kurtosis imaging (2011, methodology): “This is in contrast to other advanced diffusion models, based on high b-value and/or many gradient directions, aiming to characterize the axon diameter, diameter distribution or fiber orientation distribution (Alexander et al., 2010; Assaf et al., 2008; Barazany et al., 2009; Jespersen et al., 2010)”
Compartment models of the diffusion MR signal in brain white matter: A taxonomy and comparison (2012, neutral): “The taxonomy includes models from previous studies such as " BallStick " (Behrens et al., 2003), CHARMED (Assaf and Basser, 2005; Assaf et al., 2008) as used in AxCaliber, which is the " TensorGDRCylinders " model, the simplified version of CHARMED as used in Alexander (2008), which is the " Zeppeli”
SANDI: A compartment-based model for non-invasive apparent soma and neurite imaging by diffusion MRI (2019, neutral): “…similar to previous works (Jespersen et al., 2007; Zhang et al., 2012; Fieremans et al., 2011; Kaden et al., 2016; Assaf and Basser, 2005; Assaf et al., 2008; Alexander et al., 2010; Stanisz et al., 1997; Yablonskiy et al., 2003), we identify an intra-cellular and an extra-cellular…”
Orientationally invariant indices of axon diameter and density from diffusion MRI (2010, methodology): “The simpler CHARMED model (Assaf et al., 2004, 2008; Assaf and Basser, 2005) has only two compartments: impermeable, parallel cylindrical axons in a homogeneous extracellular space.”