Endoscopic Mucosal Resection

By B. Rembacken, Takuji Gotoda, Takahiro Fujii, A. Axon. Endoscopy, 2001

649 citations recorded by the source corpus.

We are now finding more malignancies in their early stages than previously. Attempts to ablate these lesions are difficult and do not provide the histological information required to decide on further treatment. Surgery is difficult to justify, as only a minority of lesions are associated with lymph node metastases and lesions may not become clinically relevant within the lifetime of an elderly patient. Endoscopic mucosal resection allows cancers to be resected at minimal cost, morbidity and mortality. It is also the most reliable investigation when assessing lesions which are suspicious for containing early cancer. After endoscopic removal, histological assessment of depth of penetration and a search for invasion into lymphatics or venules allows the risk of microscopic lymph node metastases to be predicted. The risk of developing metastatic disease can then be balanced against the risks of surgery in view of the patient's age and health.

Subfields: Pulmonary and Respiratory Medicine, Surgery

View Paper: https://www.semanticscholar.org/paper/be4581732a449c76a7c1aaaae20f0a7f5ebdd14b

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Citations in the corpus

• Colorectal polypectomy and endoscopic mucosal resection (EMR): European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline (2017, background): “The ideal submucosal injectate should provide a sustained lift, facilitate en bloc or oligo-piecemeal resection, be inexpensive, widely available, and have few adverse effects [134].”
• Endoscopic submucosal dissection for early gastric cancer: a large-scale feasibility study (2008, background): “Endoscopic mucosal resection (EMR) is widely accepted as a standard treatment for EGC with nominal risk of lymph node metastasis, as it is minimally invasive, safe and convenient.(3) 4 At present, the standard guideline criteria for EMR, which were established by the Japanese Gastric Cancer Associat”
• Prevalence of nonpolypoid (flat and depressed) colorectal neoplasms in asymptomatic and symptomatic adults. (2008, background): “Rectum 4 (2) 0 115 (9) 14 (17) 310 (27)”
• Clinical outcome of endoscopic submucosal dissection versus endoscopic mucosal resection of large colorectal tumors as determined by curative resection (2010, methodology): “snare (10-mm or 25-mm snare master or 20-mm spiral snare; Olympus) as described in previous reports [1–3, 6, 7].”