NF-kappaB activation by reactive oxygen species: fifteen years later.
By G. Gloire, S. Legrand-Poels, J. Piette. Biochemical Pharmacology, 2006
635 citations recorded by the source corpus.
View Paper: https://www.semanticscholar.org/paper/be1c0b02f129c7edd42850f5ed3105eabae929d2
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- Subash C. Gupta
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Citations in the corpus
- Inhibiting NF-κB Activation by Small Molecules As a Therapeutic Strategy (2010, unknown): “Antioxidants have been suggested to inhibit NF-κB activation by scavenging reactive oxygen intermediates that act as signaling molecules to activate the NF-κB pathway and by directly inhibiting IKK kinase activity by modifying critical Cys residues in the IKK kinase activation loop [146,147].”
- TNF-α and adipocyte biology (2007, background): “Indeed, it has been suggested that production of reactive oxygen species (ROS) contributes to both TNF-ainduced NFjB activation [101] and TNF-a-induced insulin”
- Hydrogen peroxide sensing, signaling and regulation of transcription factors (2014, background): “Concerning the most abundant form of NF-B, the dimer p65-p50, H2O2 is considered a modulator of activation induced by other agents, namely cytokines, and not an inducer per se [115][22][263].”
- NF-κB in Oxidative Stress (2017, background): “The role of ROS in NF-κB activation by inflammatory cytokines and LPS has been the focus of several studies, and has revealed different mechanisms for different stimuli [9].”
- Oxidative stress, inflammation, and cancer: how are they linked? (2010, background): “The mechanism for activation of NF-κB by ROS is not clear, and the relationship between NF-κB and ROS is complex [123].”
- Macrophage activation and its role in repair and pathology after spinal cord injury. (2015, background): “…the activation process of M1 macrophages, in part, through NF-κB (nuclear factor-kappa light-chainenhancer of activated-B cells) (Brüne et al., 2013), however, specific ROS effects are difficult to discern, mainly due to the nonspecific effects of the antioxidants available (Gloire et al., 2006).”