High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.
By J. Youn, Wade H Dunham, Seo Jung Hong, J. Knight, M. Bashkurov, Ginny I. Chen, H. Bagci, B. Rathod, G. Macleod, Simon W M Eng and 5 more. Molecules and Cells, 2018
690 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/bd76f8946eac275a168002548237339af014d943
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In Molecular Biology
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Citations in the corpus
- A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA (2020, methodology): “While the smaller ones resemble the granule-like particles previously detected in unstressed conditions (Youn et al., 2018), the larger punctate structures were identified as P-bodies based on their colocalization with EDC4, a P-body marker (Figure 2D).”
- G3BP1 is a tunable switch that triggers phase separation to assemble stress granules (2020, neutral): “A uthor M anuscript A uthor M anuscript A uthor M anuscript A uthor M anuscript REAGENT or RESOURCE SOURCE IDENTIFIER Deposited Data Experimental Models: Cell Lines Human: U-2 OS ATCC HTB-96 Experimental Models: Organisms/Strains Oligonucleotides gRNA sequence for SG gene KO ATXN2 AAAGTACAGAATCCAGT ”
- RNase L Amplifies Interferon Signaling by Inducing Protein Kinase R-Mediated Antiviral Stress Granules (2020, background): “Complex RNAprotein interactions in the SGs establish a liquid-liquid phase separation from the rest of the cytoplasm, facilitating recruitment of multiple proteins into a dynamic compartment (27).”
- Competing protein-RNA interaction networks control multiphase intracellular organization (2020, positive): “In contrast, UBAP2/2L 2KO results in smaller SGs, which form in only a minority of cells (Figure 2G), a finding supported by others (Cirillo et al., 2020; Huang et al., 2020; Markmiller et al., 2018; Yang et al., 2020; Youn et al., 2018).”