Genetic manipulation of lignin reduces recalcitrance and improves ethanol production from switchgrass

By C. Fu, Jonathan R. Mielenz, Xirong Xiao, Y. Ge, C. Hamilton, Miguel Rodriguez, Fang Chen, M. Foston, A. Ragauskas, J. Bouton and 2 more. Proceedings of the National Academy of Sciences of the United States of America, 2011

647 citations recorded by the source corpus.

Subfields: Agronomy and Crop Science, Biomedical Engineering, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/bd4c8c408084e6ba5a2e02602f8df5fa17e27ba0

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Citations in the corpus

Potential of Plants from the Genus Agave as Bioenergy Crops (2012, background): “manipulating cell wall polymers [6, 16, 22], or enhancing specific valuable by-product levels.”
The Switchgrass Genome: Tools and Strategies (2011, methodology): “Furthermore, the COMT-downregulated lines require reduced pretreatment severity and 300 to 400% lower cellulase dosages for equivalent product yields using simultaneous saccharifi cation and fermentation with yeast (Fu et al., 2011a).”
Switchgrass Breeding, Genetics, and Genomics (2012, background): “[85]) and the ecological community more cautious and concerned about limiting impacts outside of agricultural fields (e.”
Agricultural residue production and potentials for energy and materials services (2014, background): “On one hand crop residues are considered a favorable feed-stock for ethanol production due to the relatively low lignin content [74] and low recalcitrance to bioconversion compared to more lignified material [75,76].”
Biomass Characterization: Recent Progress in Understanding Biomass Recalcitrance (2012, positive): “25 Though in this case successful, the strategy suffers from a significant lack of information pertaining to which genes to alter and how those manipulations may not only alter recalcitrance, but also other cell wall properties critical to plant development and function.”
Lignocellulosic biomass: Biosynthesis, degradation, and industrial utilization (2016, background): “This results in an increase in ethanol yield with concomitant lower requirements of enzymes during simultaneous saccharification and fermentation [89].”