MOF-derived Co3O4@Co-Fe oxide double-shelled nanocages as multi-functional specific peroxidase-like nanozyme catalysts for chemo/biosensing and dye degradation

By Qiumeng Chen, Xiaodan Zhang, Siqi Li, J. Tan, Chengji Xu, Yuming Huang. Chemical Engineering Journal, 2020

229 citations recorded by the source corpus.

Abstract Nanozymes are attractive alternatives to natural enzymes due to their high stability and low cost. However, it is still a great challenge to acquire highly active, specific, and multi-functional nanozyme catalysts for chemo/biosensing and peroxymonosulfate (PMS) activation to degrade toxic dye pollutants. Metal-organic frameworks are attractive templates to construct multi-functional catalysts. Herein, Co3O4@Co-Fe oxide double-shelled nanocages (DSNCs) were prepared via anion-exchange combined with low-temperature pyrolysis by using ZIF-67 as a starting template. They maximized the advantages of a hollow nanostructure, acting as both nanoreactor and substrate channel, to mimic enzymes. This enables high peroxidase-like activity and very weak oxidase-like activity. The Km value of Co3O4@Co-Fe oxide DSNCs for H2O2 was 1.38 and 3.33-fold lower than those of single-shelled Co-Fe oxide and Co3O4 nanozymes, respectively. The high peroxidase-like activity of Co3O4@Co-Fe oxide DSNCs enabled H2O2 linear detection over the range 0.02 to 600 μM, with a detection limit of 20 nM. When coupled with the acetylcholinesterase/acetylthiocholine cascade enzymatic reaction, we proposed an ultra-sensitive colorimetric platform for acetylcholinesterase activity screening in the linear range over 8 × 10−4–1 mU mL−1, with a detection limit of 2 × 10−4 mU mL−1. The Co3O4@Co-Fe oxide DSNCs can active PMS to degrade 99.1% of acid fuchsin within 20 min, along with good reusability over ten-cycle run. The kinetics of 15 mg L−1 acid fuchsin degradation was 0.176 min−1 at 25 °C with 300 mg L−1 PMS and 150 mg L−1 DSNCs. This work details the attractive applications of DSNCs for chemo/biosensing and dye degradation.

Subfields: Electrical and Electronic Engineering, Materials Chemistry

View Paper: https://www.semanticscholar.org/paper/bd291c5a892be3b9773c5e7c9ee56d086ae9f1a6