Synaptic connections of dentate granule cells and hilar neurons: results of paired intracellular recordings and intracellular horseradish peroxidase injections.

By H. Scharfman, D. D. Kunkel, P. Schwartzkroin. 1990

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Nonrandom Local Circuits in the Dentate Gyrus (2008, background): “Analyzing responses to imprecisely timed trains of presynaptic APs, as in previous studies (Scharfman et al., 1990; Scharfman, 1995), Received July 31, 2008; revised Sept. 17, 2008; accepted Oct. 6, 2008.”
Effects of adult-generated granule cells on coordinated network activity in the dentate gyrus (2010, background): “Such inputs however are typically more robust than those onto CA3 pyramidal cells (Scharfman et al., 1990; Mori et al., 2004, 2007) and therefore may be relevant at earlier stages than the specialized mossy fiber synapses, while young neurons are still highly excitable.”
Reactivation of neuronal ensembles in hippocampal dentate gyrus during sleep after spatial experience (1998, background): “There is also electrophysiological and anatomical evidence which suggests that both the connections from granule cells to mossy cells and the connections from mossy cells to granule cells are excitatory (Scharfman 1994b; Scharfman 1995; Scharfman et al. 1990; Wenzel et al. 1997).”
Pattern Separation in the Dentate Gyrus: A Role for the CA3 Backprojection (2010, result): “This is consistent with empirical data showing that the quantal size of giant mossy fiber boutons is extremely large, so summation of a few inputs is likely to be sufficient to cause action potential generation (Scharfman et al., 1990; Henze et al., 2000).”